Rat ALK-1 / ACVRL1 Protein (His & Fc Tag) 10596-R03H from Sino Biological, Inc. | Biocompare.com

Supplier Images

Rat ALK-1 / ACVRL1 Protein (His & Fc Tag)

Rat ALK-1 / ACVRL1 Protein (His & Fc Tag)

Be the first to write a review!

Supplier Page from
Sino Biological, Inc. for
Rat ALK-1 / ACVRL1 Protein (His & Fc Tag)

Description

A synthetic DNA sequence encoding the rat ACVRL1 (NP_071886.1) extracellular domain (Met 1-Ala 118) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus

Product Specs
ItemRat ALK-1 / ACVRL1 Protein (His & Fc Tag)
CompanySino Biological, Inc.
Price Supplier Page View Company Product Page
Catalog Number10596-R03H
Conjugate/TagC-human IgG1-Fc, His
Purity> 90 % as determined by SDS-PAGE
TypeRecombinant protein
Molecular WeightThe secreted recombinant rat ACVRL1/Fc is a disulfide-linked homodimer after removal of the signal peptide. The reduced monomer comprises 343 amino acids with a predicted molecular mass of 38.7 kDa. As a result of glycosylation, it migrates as an approximately 50-55 kDa band in SDS-PAGE under reducing conditions
SpeciesRat
Molecule NameACVRL1
Source/Expression SystemHEK293 Cells
NCBI Full Gene Nameactivin A receptor like type 1
NCBI Gene AliasesAlk1, R-3, R3, SETHKIR
ActivityMeasured by its ability to inhibit BMP9-induced alkaline phosphatase production by MC3T3E1 mouse chondrogenic cells. David, L. et al. (2007) Blood 109:1953. The ED50 for this effect is typically 40-200 ng/mL in the presence of 2 ng/mL of recombinant human BMP9
FormatLyophilized from sterile PBS, pH 7.4

Add to Compare List

Sino Biological, Inc.

Sino Biological, Inc.

1400 Liberty Ridge Drive

Suite 101

Wayne, PA 19087

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: http://www.sinobiological.com/

Be the First to Write a Review!